Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.56 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.56 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.56 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MPO | P05164 | 2/20 | 0.50 |
| ▸ | XDH | P47989 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31195781 | 1.00 | KDM4E (0.61) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D | |
| SCHEMBL7983972 | 0.85 | KDM4E (0.77) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL7983954 | 0.83 | ALDH1A1 (0.70) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D | |
| SCHEMBL31188762 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL4256786 | 0.81 | GRIN2D (0.60) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D | |
| SCHEMBL31609272 | 0.81 | MAPT (0.49) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D | |
| SCHEMBL31744504 | 0.81 | GRIN2D (0.60) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D | |
| SCHEMBL12328354 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D | |
| SCHEMBL31609245 | 0.81 | GRIN2D (0.60) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D | |
| SCHEMBL8944835 | 0.80 | PDE3B (0.52) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250185446-A1 | HOLE-TRANSPORTING SELF-ORGANISED MONOLAYER FOR PEROVSKITE SOLAR CELLS | HELMHOLTZ-ZENTRUM BERLIN FÜR MATERIALIEN UND ENERGIE GMBH (DE) | 2025-06-05 | — | — | US | disclosed |
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0586608-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |