SCHEMBL8944889

SCHEMBL8944889

CCCC1CCC(c2ccc(-c3ccc(-c4ccc(OCC)c(F)c4F)cc3)cc2F)CO1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 6/20 0.34
NAAA Q02083 1/20 0.32
FGFR1 P11362 1/20 0.31
FGFR2 P21802 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2B Q13224 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
SLC6A2 P23975 2/20 0.30
SLC6A4 P31645 2/20 0.30
SLC6A3 Q01959 1/20 0.30
PTGDR2 Q9Y5Y4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18718212 0.96 FPR2 (0.37) FPR2NAAAFGFR1FGFR2GRIN1
SCHEMBL12023979 0.95 FPR2 (0.36) FPR2NAAAFGFR1FGFR2GRIN1
SCHEMBL8944839 0.94 FPR2 (0.36) FPR2FFAR4
SCHEMBL8945178 0.93 RARB (0.33) FPR2FFAR4
SCHEMBL12999976 0.93 FPR2 (0.31) FPR2
SCHEMBL8945177 0.93 FPR2 (0.33) FPR2NAAAFGFR1FGFR2SLC6A2
SCHEMBL8944909 0.93 FPR2 (0.35) FPR2
SCHEMBL8945609 0.93 FPR2 (0.33) FPR2NAAASLC6A2SLC6A4SLC6A3
SCHEMBL8945032 0.92 FPR2 (0.36) FPR2NAAAGRIN1GRIN2BSLC6A2
SCHEMBL8945183 0.92 FPR2 (0.35) FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed