Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2269285 | 1.00 | TACR1 (0.51) | TACR1MMEACECPA1ACE2 | |
| SCHEMBL9852735 | 0.85 | ANPEP (0.49) | MMEACECPA1ACE2CTNNB1 | |
| SCHEMBL9727658 | 0.82 | CTNNB1 (0.45) | MMEACECPA1ACE2CTNNB1 | |
| SCHEMBL9631571 | 0.82 | CTNNB1 (0.45) | MMEACECPA1ACE2CTNNB1 | |
| SCHEMBL27922304 | 0.81 | ACACB (0.57) | TACR1MMEACECPA1ACE2 | |
| SCHEMBL27922307 | 0.81 | ACACB (0.57) | TACR1MMEACECPA1ACE2 | |
| SCHEMBL7856008 | 0.80 | ACACB (0.44) | CTSSACACBMEN1KMT2A | |
| SCHEMBL2761181 | 0.79 | MME (0.63) | TACR1MMEACECPA1ACE2 | |
| SCHEMBL8673871 | 0.79 | MME (0.63) | TACR1MMEACECPA1ACE2 | |
| SCHEMBL3659382 | 0.79 | MME (0.63) | TACR1MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508383-A | Cyclic peptide LHRH antagonists | TAP HOLDINGS INC. (US) | 1996-04-16 | — | — | US | disclosed |
| WO-1995024424-A1 | CYCLIC PEPTIDE LHRH ANTAGONISTS | ABBOTT LABORATORIES (US) | 1995-09-14 | — | — | WO | disclosed |