Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2269285 | 0.85 | TACR1 (0.51) | ANPEPMMEACECPA1ACE2 | |
| SCHEMBL8944896 | 0.85 | TACR1 (0.51) | ANPEPMMEACECPA1ACE2 | |
| SCHEMBL7445995 | 0.79 | NPC1 (0.49) | ANPEPCTSSCTSK | |
| SCHEMBL9852737 | 0.79 | CASP1 (0.48) | ANPEPMMEACECPA1ACE2 | |
| SCHEMBL9631571 | 0.79 | CTNNB1 (0.45) | MMEACECPA1ACE2CTSS | |
| SCHEMBL9727658 | 0.79 | CTNNB1 (0.45) | MMEACECPA1ACE2CTSS | |
| SCHEMBL27869245 | 0.79 | ANPEP (0.67) | ANPEPMMP9MMP8MMP2MEN1 | |
| SCHEMBL10588292 | 0.76 | FAAH (0.46) | MMEACECPA1ACE2CTSS | |
| SCHEMBL10588293 | 0.76 | FAAH (0.46) | MMEACECPA1ACE2CTSS | |
| SCHEMBL6443448 | 0.75 | CTSS (0.46) | MMEACECPA1ACE2CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | claimed |