Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395276 | 0.93 | PPARG (0.59) | AGTR2AGTR1PPARG | |
| SCHEMBL8396532 | 0.91 | AGTR2 (0.48) | AGTR2AGTR1 | |
| SCHEMBL9042835 | 0.89 | AGTR2 (0.45) | AGTR2AGTR1 | |
| Trifluoroacetic Acid SCHEMBL8944378 | 0.89 | PPARG (0.55) | AGTR2AGTR1PPARG | |
| SCHEMBL8394862 | 0.86 | AGTR2 (0.65) | AGTR2AGTR1PPARG | |
| SCHEMBL8392002 | 0.86 | PPARG (0.60) | AGTR2AGTR1PPARG | |
| SCHEMBL8391535 | 0.85 | PPARG (0.62) | AGTR2AGTR1PPARG | |
| SCHEMBL9040465 | 0.85 | TLR7 (0.44) | AGTR2AGTR1 | |
| SCHEMBL9872309 | 0.85 | AGTR2 (0.61) | AGTR2AGTR1 | |
| SCHEMBL8391844 | 0.84 | PPARG (0.49) | AGTR2AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |