SCHEMBL8944964

SCHEMBL8944964

Cc1ccc(OC(=O)/C=C\C(=O)Oc2ccccc2C)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.49
KDM4E B2RXH2 1/20 0.49
HPGD P15428 1/20 0.49
HSD17B10 Q99714 1/20 0.49
LMNA P02545 2/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
ATM Q13315 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ALDH1A1 P00352 1/20 0.42
KMT2A Q03164 2/20 0.42
PTK2B Q14289 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
MAOB P27338 1/20 0.40
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
DRD3 P35462 1/20 0.40
BCHE P06276 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11556996 0.89 KDM4E (0.58) MAPTKDM4EHPGDHSD17B10LMNA
SCHEMBL8166076 0.89 KDM4E (0.58) MAPTKDM4EHPGDHSD17B10LMNA
SCHEMBL10339829 0.89 KDM4E (0.58) MAPTKDM4EHPGDHSD17B10LMNA
SCHEMBL20024204 0.84 LMNA (0.56) MAPTHPGDLMNAL3MBTL1ALDH1A1
SCHEMBL17576048 0.84 LMNA (0.56) MAPTHPGDLMNAL3MBTL1ALDH1A1
SCHEMBL8998925 0.84 LMNA (0.64) HPGDLMNAL3MBTL1ATMTDP1
SCHEMBL8166082 0.84 LMNA (0.64) HPGDLMNAL3MBTL1ATMTDP1
SCHEMBL8998922 0.84 LMNA (0.64) HPGDLMNAL3MBTL1ATMTDP1
SCHEMBL8166087 0.83 KDM4E (0.56) MAPTKDM4EHPGDHSD17B10LMNA
SCHEMBL8166080 0.83 KDM4E (0.56) MAPTKDM4EHPGDHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5523337-A CURABLE THERMOSETTING RESIN COMPRISING UNSATURATED ESTER, OLEFIN MONOMER, LOW PROFILE ADDITIVE, MOLD RELEASE AGENT, AND BLOCK COPOLYMER OF UNSATURATED POLYESTER AND DIISOCYANATE FUNCTIONAL POLYMER; STRESS RESISTANCE GENCORP INC. (US) 1996-06-04 US disclosed
US-5498763-A NONCRACKING GENCORP INC. (US) 1996-03-12 US disclosed
US-5491184-A MIXING COMPATIBLE BLOCK COPOLYMER INTO UNSATURATED POLYESTER RESIN COMPOSITION TO TOUGHEN GENCORP. INC. (US) 1996-02-13 US disclosed
EP-0662501-A1 Polymeric compositions, their preparation and use GENCORP INC. (US) 1995-07-12 EP disclosed
US-5428068-A Addition-condensation block polymers GENCORP INC. (US) 1995-06-27 US disclosed
US-5389443-A Improved elongation, flexibility; for fiber reinforced plastics GENCORP INC. (US) 1995-02-14 US disclosed
US-5385963-A Unsaturated polyester-modified flexible copolymers for use in sheet molding compositions GENCORP INC. (US) 1995-01-31 US disclosed
US-5362819-A Polyester-flexible polymer block copolymers and mixtures thereof GENCORP INC. (US) 1994-11-08 US disclosed
EP-0612786-A1 Polyester-flexible polymer block copolymers and mixtures thereof GENCORP INC. (US) 1994-08-31 EP disclosed
EP-0612787-A1 Polyester-flexible polymer block copolymer coated fiber structures and utilization thereof in a polymer matrix GENCORP INC. (US) 1994-08-31 EP disclosed
US-5334441-A Tough, noncracking, flexible sheet molding materials, for automobile panels, aircraft, housings GENCORP INC. (US) 1994-08-02 US disclosed