Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | SCN4A | P35499 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8945374 | 0.99 | FAAH (0.52) | FAAHMGLLSCN4ACYP3A4CYP1A2 | |
| SCHEMBL8945016 | 0.88 | FAAH (0.56) | FAAHMGLLSCN4ACYP3A4CYP1A2 | |
| SCHEMBL8944958 | 0.87 | FAAH (0.53) | FAAHMGLLSCN4ACYP3A4CYP1A2 | |
| SCHEMBL8945321 | 0.84 | FAAH (0.52) | FAAHMGLLCYP3A4CA12CA1 | |
| SCHEMBL8945055 | 0.83 | FAAH (0.51) | FAAHMGLLCYP3A4CA12CA1 | |
| SCHEMBL8945307 | 0.82 | FAAH (0.57) | FAAHMGLLCYP3A4CA12CA1 | |
| SCHEMBL8945289 | 0.81 | FAAH (0.48) | FAAHMGLLSCN4ACYP3A4CYP1A2 | |
| SCHEMBL8944998 | 0.80 | FAAH (0.58) | FAAHMGLLSCN4ACYP3A4CA12 | |
| SCHEMBL8945199 | 0.80 | FAAH (0.51) | FAAHMGLLCYP3A4CA12CA1 | |
| Hydrochloric Acid SCHEMBL8945355 | 0.80 | FAAH (0.55) | FAAHMGLLCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |