Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 11/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945088 | 1.00 | KCNN4 (0.40) | KCNN4KIF11TRPA1CYP3A4MAPK1 | |
| SCHEMBL2792114 | 0.85 | KCNN4 (0.37) | KCNN4ALDH1A1 | |
| SCHEMBL2792112 | 0.85 | KCNN4 (0.37) | KCNN4ALDH1A1 | |
| SCHEMBL7479981 | 0.85 | KCNN4 (0.43) | KCNN4KIF11TRPA1CYP3A4MAPK1 | |
| SCHEMBL3856980 | 0.82 | KCNN4 (0.47) | KCNN4KIF11TRPA1ALDH1A1 | |
| SCHEMBL3302423 | 0.82 | KCNN4 (0.47) | KCNN4KIF11TRPA1ALDH1A1 | |
| SCHEMBL3302429 | 0.82 | KCNN4 (0.47) | KCNN4KIF11TRPA1ALDH1A1 | |
| SCHEMBL10029077 | 0.79 | KCNN4 (0.44) | KCNN4KIF11TRPA1CYP3A4MAPK1 | |
| SCHEMBL7312975 | 0.79 | TRPA1 (0.41) | KCNN4KIF11TRPA1CYP3A4MAPK1 | |
| SCHEMBL7317772 | 0.79 | TRPA1 (0.41) | KCNN4KIF11TRPA1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |