Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806998 | 0.94 | CYP4F2 (0.43) | CYP4F2CYP4A11KDM4EHPGDHSD17B10 | |
| SCHEMBL9105956 | 0.91 | CYP4F2 (0.47) | CYP4F2CYP4A11KDM4EHPGDHSD17B10 | |
| SCHEMBL25240413 | 0.85 | CYP4F2 (0.43) | CYP4F2CYP4A11KDM4EHPGDHSD17B10 | |
| SCHEMBL3906109 | 0.80 | CYP4F2 (0.53) | CYP4F2CYP4A11KDM4EHPGDHSD17B10 | |
| SCHEMBL1746633 | 0.80 | KDM4E (0.48) | CYP4F2CYP4A11KDM4EHPGDHSD17B10 | |
| SCHEMBL12984187 | 0.78 | CYP4F2 (0.45) | CYP4F2CYP4A11KDM4EHPGDHSD17B10 | |
| SCHEMBL3623961 | 0.78 | CYP4F2 (0.45) | CYP4F2CYP4A11KDM4EHPGDHSD17B10 | |
| SCHEMBL29056374 | 0.78 | CYP4F2 (0.47) | CYP4F2CYP4A11KDM4EHPGDHSD17B10 | |
| SCHEMBL512668 | 0.77 | LMNA (0.43) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL1745188 | 0.77 | TAAR1 (0.53) | CYP4F2CYP4A11KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538988-A | CARDIOVASCULAR DISORDERS AND DOPAMINE HYDROLASE ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. | 1996-07-23 | — | — | US | disclosed |