SCHEMBL8945127

SCHEMBL8945127

CCCCCC1(Cc2ccc(N)cc2)CCCC(c2ccccc2C)C1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 10/20 0.32
HTR2C P28335 2/20 0.32
BACE1 P56817 1/20 0.31
BACE2 Q9Y5Z0 1/20 0.31
HDAC4 P56524 1/20 0.31
HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8945274 0.99 CYP19A1 (0.33) CYP19A1HTR2CBACE1BACE2HDAC4
SCHEMBL8945226 0.99 CYP19A1 (0.33) CYP19A1HTR2CBACE1BACE2HDAC4
SCHEMBL8945363 0.99 CYP19A1 (0.33) CYP19A1HTR2CBACE1BACE2HDAC4
SCHEMBL8945008 0.97 HTR2C (0.32) CYP19A1HTR2CHDAC4HTR6
SCHEMBL8945195 0.92 HTR2C (0.33) HTR2CHDAC4HTR6
SCHEMBL8945139 0.88 HTR2C (0.38) CYP19A1HTR2CHDAC4HTR6
SCHEMBL8945404 0.88 HTR2C (0.35) HTR2CHDAC4HTR6
SCHEMBL8945288 0.87 HTR2C (0.37) CYP19A1HTR2CHTR6
SCHEMBL8945379 0.87 HTR2C (0.37) CYP19A1HTR2CHTR6
SCHEMBL8945242 0.87 HTR2C (0.37) CYP19A1HTR2CHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5501884-A Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1996-03-26 US disclosed