Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945242 | 0.99 | HTR2C (0.37) | HTR2CCYP19A1HTR6OPRM1OPRD1 | |
| SCHEMBL8945288 | 0.99 | HTR2C (0.37) | HTR2CCYP19A1HTR6OPRM1OPRD1 | |
| SCHEMBL8945379 | 0.99 | HTR2C (0.37) | HTR2CCYP19A1HTR6OPRM1OPRD1 | |
| SCHEMBL8945021 | 0.96 | HTR2C (0.38) | HTR2CCYP19A1HTR6OPRM1OPRD1 | |
| SCHEMBL8945208 | 0.91 | HTR2C (0.40) | HTR2CCYP19A1HTR6OPRL1MMP2 | |
| SCHEMBL8945127 | 0.88 | CYP19A1 (0.32) | HTR2CCYP19A1HTR6HDAC4 | |
| SCHEMBL8945420 | 0.88 | HTR2C (0.41) | HTR2CHTR6OPRL1MMP2MMP13 | |
| SCHEMBL8945274 | 0.87 | CYP19A1 (0.33) | HTR2CCYP19A1MMP2MMP9MMP8 | |
| SCHEMBL8945226 | 0.87 | CYP19A1 (0.33) | HTR2CCYP19A1MMP2MMP9MMP8 | |
| SCHEMBL8945363 | 0.87 | CYP19A1 (0.33) | HTR2CCYP19A1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |