Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945307 | 0.85 | FAAH (0.57) | FAAHMGLLACHECA12CA1 | |
| Hydrochloric Acid SCHEMBL8945101 | 0.84 | FAAH (0.49) | FAAHMGLLACHECA12CA1 | |
| Hydrochloric Acid SCHEMBL8945355 | 0.83 | FAAH (0.55) | FAAHMGLLACHECA12CA1 | |
| SCHEMBL8945264 | 0.83 | FAAH (0.48) | FAAHMGLLACHESSTR4 | |
| SCHEMBL8945199 | 0.83 | FAAH (0.51) | FAAHMGLLACHECA12CA1 | |
| SCHEMBL8945055 | 0.83 | FAAH (0.51) | FAAHMGLLACHECA12CA1 | |
| Hydrochloric Acid SCHEMBL8945397 | 0.83 | FAAH (0.48) | FAAHMGLLACHECA12CA1 | |
| SCHEMBL8944998 | 0.83 | FAAH (0.58) | FAAHMGLLACHECA12CA1 | |
| SCHEMBL8945016 | 0.82 | FAAH (0.56) | FAAHMGLLACHECA12CA1 | |
| Hydrochloric Acid SCHEMBL8945358 | 0.82 | FAAH (0.57) | FAAHMGLLACHECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |