SCHEMBL8945287

SCHEMBL8945287

CCCC1(c2ccccc2Cc2ccc(N)c(F)c2)CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 9/20 0.36
SLC6A3 Q01959 8/20 0.36
RXRA P19793 1/20 0.34
CTSL P07711 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
SLC6A2 P23975 3/20 0.32
HDAC4 P56524 1/20 0.32
ESR1 P03372 1/20 0.32
S1PR1 P21453 1/20 0.31
S1PR3 Q99500 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8945516 0.87 SKP2 (0.40) SLC6A4SLC6A3RXRASLC6A2HDAC4
SCHEMBL8945020 0.87 HDAC4 (0.38) SLC6A4SLC6A3SLC6A2HDAC4
SCHEMBL8945201 0.86 SLC6A4 (0.33) SLC6A4SLC6A3SLC6A2HDAC4S1PR1
SCHEMBL8945419 0.84 RXRA (0.37) SLC6A4SLC6A3RXRACTSLCTSS
SCHEMBL8578668 0.83 SLC6A4 (0.37) SLC6A4SLC6A3SLC6A2HDAC4
SCHEMBL8945489 0.81 SKP2 (0.44) SLC6A4HDAC4
SCHEMBL8945342 0.80 SKP2 (0.43) SLC6A4SLC6A3SLC6A2HDAC4
SCHEMBL8945573 0.79 SKP2 (0.42) SLC6A4SLC6A3SLC6A2HDAC4
SCHEMBL8944988 0.79 SKP2 (0.42) SLC6A4SLC6A3SLC6A2HDAC4
SCHEMBL8945402 0.79 SKP2 (0.42) SLC6A4SLC6A3SLC6A2HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5501884-A Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1996-03-26 US disclosed