Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 7/20 | 0.40 |
| ▸ | DRD4 | P21917 | 7/20 | 0.40 |
| ▸ | DRD5 | P21918 | 7/20 | 0.40 |
| ▸ | DRD3 | P35462 | 7/20 | 0.40 |
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 6/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.34 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945256 | 1.00 | DRD1 (0.40) | DRD1DRD4DRD5DRD3DRD2 | |
| SCHEMBL8945353 | 1.00 | DRD1 (0.40) | DRD1DRD4DRD5DRD3DRD2 | |
| SCHEMBL8945156 | 0.99 | DRD1 (0.41) | DRD1DRD4DRD5DRD3DRD2 | |
| SCHEMBL8945045 | 0.95 | DRD2 (0.42) | DRD1DRD4DRD5DRD3DRD2 | |
| SCHEMBL8945086 | 0.91 | HTR2C (0.43) | DRD1DRD4DRD5DRD3DRD2 | |
| SCHEMBL8945239 | 0.87 | HTR2C (0.43) | DRD1DRD4DRD5DRD3DRD2 | |
| SCHEMBL8945278 | 0.80 | HTR2C (0.46) | DRD1DRD4DRD5DRD3DRD2 | |
| SCHEMBL8945288 | 0.80 | HTR2C (0.37) | DRD2HTR2CSPHK1OPRM1OPRD1 | |
| SCHEMBL8945242 | 0.80 | HTR2C (0.37) | DRD2HTR2CSPHK1OPRM1OPRD1 | |
| SCHEMBL8945379 | 0.80 | HTR2C (0.37) | DRD2HTR2CSPHK1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |