Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623546 | 0.86 | MEN1 (0.81) | MEN1KMT2AHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL7558815 | 0.85 | SRD5A1 (0.53) | MEN1KMT2ALTA4HLMNAL3MBTL1 | |
| SCHEMBL9302685 | 0.84 | MEN1 (1.00) | MEN1KMT2AHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL27503951 | 0.83 | MEN1 (0.76) | MEN1KMT2AHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL723132 | 0.83 | RAB9A (0.66) | KMT2ALTA4HLMNAELANEALDH1A1 | |
| SCHEMBL10515358 | 0.82 | MEN1 (0.62) | MEN1KMT2AHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL16556312 | 0.81 | KMT2A (0.71) | MEN1KMT2AHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL6459728 | 0.80 | PPARG (0.47) | KMT2ALTA4HLMNAL3MBTL1ELANE | |
| SCHEMBL11307504 | 0.80 | KMT2A (0.69) | MEN1KMT2AHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL5649619 | 0.79 | RAB9A (0.66) | MEN1KMT2ASMN1; SMN2LTA4HLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510375-A | VIRICIDES TREATING INFECTION CAUSED BY HUMAN IMMUNODEFICIENCY VIRUS AND AIDS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |