Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945454 | 0.76 | PRMT5 (0.40) | KDM4ELMNAPRMT5HTTSMN1; SMN2 | |
| SCHEMBL8945460 | 0.76 | KDM4E (0.40) | KDM4ELMNAPRMT5HTTSMN1; SMN2 | |
| SCHEMBL7238942 | 0.67 | GRM5 (0.54) | KDM4ELMNAHTTHPGDALDH1A1 | |
| SCHEMBL30096779 | 0.67 | GRM5 (0.54) | KDM4ELMNAHTTHPGDALDH1A1 | |
| SCHEMBL8945427 | 0.67 | HTT (0.74) | KDM4ELMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL17049278 | 0.66 | RPS6KA5 (0.48) | KDM4ELMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20145350 | 0.66 | TLR8 (0.62) | LMNATLR8TLR7PRMT5 | |
| SCHEMBL12510648 | 0.64 | PRMT5 (0.45) | KDM4ELMNATLR8TLR7PRMT5 | |
| SCHEMBL19520171 | 0.62 | PRMT5 (0.56) | KDM4ELMNATLR8TLR7PRMT5 | |
| SCHEMBL10998952 | 0.62 | KDM4E (0.35) | KDM4ELMNAHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494887-A | Ring annulated 5-alkoxy-n-aryl[1,2,4]triazolo[1,5-C]-pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1996-02-27 | — | — | US | disclosed |