Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 12/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL55302 | 0.79 | AXL (0.39) | AXLMKNK1MKNK2ADORA2AADORA1 | |
| SCHEMBL29893499 | 0.79 | AXL (0.39) | AXLMKNK1MKNK2ADORA2AADORA1 | |
| SCHEMBL4714518 | 0.72 | ADORA2A (0.56) | AXLMKNK1MKNK2ADORA2AADORA1 | |
| SCHEMBL8363046 | 0.72 | ADORA2A (0.42) | AXLMKNK1MKNK2ADORA2AADORA1 | |
| SCHEMBL9381944 | 0.72 | ADORA2A (0.56) | ADORA2AADORA1ADORA3ADORA2BELANE | |
| SCHEMBL18701478 | 0.72 | ADORA2A (0.56) | AXLMKNK1MKNK2ADORA2AADORA1 | |
| SCHEMBL8945303 | 0.72 | HTT (0.61) | AXLMKNK1MKNK2ADORA2AADORA1 | |
| SCHEMBL7121620 | 0.71 | PDE4A (0.55) | ADORA2AADORA1HTTMAPTPIK3CA | |
| SCHEMBL14095091 | 0.69 | PDE4A (0.52) | ADORA2AADORA1PIK3CAMTOR | |
| SCHEMBL14095195 | 0.69 | ADORA2A (0.50) | ADORA2AADORA1HTTMAPTADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494887-A | Ring annulated 5-alkoxy-n-aryl[1,2,4]triazolo[1,5-C]-pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1996-02-27 | — | — | US | disclosed |