Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431669 | 0.81 | CYP1A2 (0.45) | HTTMAPTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL5313545 | 0.80 | HTT (0.63) | HTTMAPTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL11988229 | 0.76 | HTT (0.58) | HTTMAPTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL29893499 | 0.75 | AXL (0.39) | HTTMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL55302 | 0.75 | AXL (0.39) | HTTMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL8945427 | 0.75 | HTT (0.74) | HTTMAPTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL14103786 | 0.74 | MTOR (0.40) | HTTMAPTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL8945519 | 0.72 | AXL (0.37) | HTTMAPTMAPK1AXLMKNK1 | |
| SCHEMBL13236422 | 0.72 | ADORA2A (0.53) | HTTMAPTL3MBTL1RXFP1SMN1; SMN2 | |
| SCHEMBL17175794 | 0.71 | L3MBTL1 (0.55) | HTTMAPTL3MBTL1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494887-A | Ring annulated 5-alkoxy-n-aryl[1,2,4]triazolo[1,5-C]-pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1996-02-27 | — | — | US | disclosed |