Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8111887 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HSD17B10RAB9ANPC1CKS1B | |
| SCHEMBL9641291 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HSD17B10RAB9ANPC1CKS1B | |
| SCHEMBL8945647 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HSD17B10RAB9ANPC1CKS1B | |
| SCHEMBL9642664 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HSD17B10RAB9ANPC1CKS1B | |
| SCHEMBL9642157 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HSD17B10RAB9ANPC1CKS1B | |
| SCHEMBL9535407 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HSD17B10RAB9ANPC1CKS1B | |
| SCHEMBL9642141 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HSD17B10RAB9ANPC1CKS1B | |
| SCHEMBL8103143 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HSD17B10RAB9ANPC1CKS1B | |
| SCHEMBL9641813 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HSD17B10RAB9ANPC1CKS1B | |
| SCHEMBL9640970 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HSD17B10RAB9ANPC1CKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494887-A | Ring annulated 5-alkoxy-n-aryl[1,2,4]triazolo[1,5-C]-pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1996-02-27 | — | — | US | disclosed |