Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.44 |
| ▸ | ACR | P10323 | 6/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HGFAC | Q04756 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | C1R | P00736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10536307 | 0.86 | TRPA1 (0.45) | PRSS1ACRF2PRSS2PRSS3 | |
| SCHEMBL9777755 | 0.82 | PRSS1 (0.59) | PRSS1ACRF2PRSS2PRSS3 | |
| SCHEMBL8945764 | 0.82 | PRSS1 (0.59) | PRSS1ACRF2PRSS2PRSS3 | |
| SCHEMBL1404357 | 0.82 | PRSS1 (0.59) | PRSS1ACRF2PRSS2PRSS3 | |
| SCHEMBL14016851 | 0.81 | KMT2A (0.58) | PRSS1ACRMAPTKDM4EPOLB | |
| SCHEMBL10042169 | 0.80 | KMT2A (0.61) | PRSS1ACRMAPTPOLBKMT2A | |
| SCHEMBL31086840 | 0.80 | KDM4E (0.48) | MAPTKDM4EPOLBMAPK1KMT2A | |
| SCHEMBL496061 | 0.80 | KDM4E (0.48) | MAPTKDM4EPOLBMAPK1KMT2A | |
| SCHEMBL14405887 | 0.79 | MAPT (0.45) | MAPTKDM4EPOLBMAPK1KMT2A | |
| SCHEMBL8623449 | 0.79 | MAPT (0.45) | MAPTKDM4EPOLBMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569727-A | REACTING A DIEPOXIDE WITH A DIISOCYANATE IN PRESENCE OF POLYMERIZATION CATALYST WHICH IS A COMPLEX OF LEWIS ACID AND LEWIS BASE AND BAKING | EUROPEAISCHE WIRTSCHAFTSGEMEINSCHAFT (LU) | 1996-10-29 | — | — | US | disclosed |