Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9582709 | 0.87 | KMT2A (0.54) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL10936231 | 0.87 | NPC1 (0.63) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL9582743 | 0.87 | MAOB (0.59) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL28337088 | 0.85 | ALDH1A1 (0.55) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL74692 | 0.84 | CYP1A2 (0.62) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL9582403 | 0.84 | NPC1 (0.68) | MAOAMAOBMEN1KMT2ANPC1 | |
| SCHEMBL30751161 | 0.84 | NPC1 (0.68) | MAOAMAOBMEN1KMT2ANPC1 | |
| SCHEMBL19329494 | 0.83 | CYP1A2 (0.70) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL9690178 | 0.82 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2530464 | 0.82 | CYP1A2 (0.60) | MEN1KMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-64000055-A | — | — | None | — | — | JP | disclosed |
| US-20120288885-A1 | METHOD AND KIT FOR MEASURING ENZYMATIC ACTIVITIES OF VARIOUS CYTOCHROME P450 MOLECULE SPECIES COMPREHENSIVELY AND WITH HIGH EFFICIENCY | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLGOY (JP) | 2012-11-15 | — | — | US | disclosed |
| CN-101484161-A | Cannabinoid receptor antagonists/iN. V.erse agonists | JENRIN DISCOVERY (US) | 2009-07-15 | — | — | CN | disclosed |
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5292760-A | 4-heteroaryl-1,3-benzodiazepines and 2-substituted-α-(heteroaryl)benzeneethanamines | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5260339-A | 4-phenyl-1,3-benzodiazepines and 2-amino-α-phenylphenethylamines for treating convulsions and protecting neurons | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-11-09 | — | — | US | disclosed |
| US-5185465-A | Carboxamides of 2-amino-alpha-phenlphenethylamines | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-02-09 | — | — | US | disclosed |
| US-4968721-A | 2-amino-alpha-phenylphenethylamines and method of use | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-11-06 | — | — | US | disclosed |
| US-4933493-A | Intermediates for the preparation of 4-phenyl-1,3-benzodiazepines | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-06-12 | — | — | US | disclosed |
| US-4855502-A | CHEMICAL INTERMEDIATES FOR 1,3-BENZODIAZEPINES | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-08-08 | — | — | US | disclosed |
| US-4504680-A | 4-Phenyl-1,3-benzodiazepines | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-03-12 | — | — | US | disclosed |
| US-4469889-A | 2-(2-Nitrophenyl)-1-phenylethanone oxime acetates | HOECHST-ROUSSEL PHARMACEUTICALS, INCORPORATED (US) | 1984-09-04 | — | — | US | disclosed |
| US-4462933-A | Process for preparing 4-phenyl-1,3-benzodiazepines | HOECHST-ROUSSEL PHARMACEUTICALS, INCORPORATED (US) | 1984-07-31 | — | — | US | disclosed |
| US-4459231-A | Process for preparing 4-phenyl-1,3-benzodiazepines | HOECHST-ROUSSEL PHARMACEUTICALS, INCORPORATED (US) | 1984-07-10 | — | — | US | disclosed |
| US-4459230-A | Process for preparing 4-phenyl-1,3-benzodiazepines | HOECHST-ROUSSEL PHARMACEUTICALS, INCORPORATED (US) | 1984-07-10 | — | — | US | disclosed |
| US-4409145-A | OXIMINATION, ESTERIFICATION, REDUCTION | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1983-10-11 | — | — | US | disclosed |
| EP-0009800-B1 | 4-PHENYL-1,3-BENZODIAZEPINES, METHOD FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THE COMPOUNDS FOR USE AS MEDICAMENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-23 | — | — | EP | disclosed |
| EP-0057870-A1 | N-optionelly substituted-2-amino-alpha-phenylphenethylamines and a method for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-08-18 | — | — | EP | disclosed |
| US-4309424-A | 4-Phenyl-1,3-benzodiazepines | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1982-01-05 | — | — | US | disclosed |
| EP-0009800-A2 | 4-Phenyl-1,3-benzodiazepines, method for their preparation, pharmaceutical compositions containing them, and the compounds for use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-16 | — | — | EP | disclosed |