Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.47 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.47 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13015660 | 0.85 | KIF11 (0.52) | ABCC9ABCC8KCNJ11KCNJ8MEN1 | |
| SCHEMBL2432349 | 0.84 | GAA (0.51) | GAAABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL14568587 | 0.84 | CFTR (0.51) | GAAMEN1KMT2AMAPTTACR1 | |
| SCHEMBL31245754 | 0.83 | CYP1A2 (0.57) | GAAMEN1KMT2AMAPTHTT | |
| SCHEMBL6063344 | 0.83 | CYP1A2 (0.57) | GAAMEN1KMT2AMAPTHTT | |
| SCHEMBL19669082 | 0.82 | MEN1 (0.57) | GAAMEN1KMT2AHTTPDK1 | |
| SCHEMBL30006263 | 0.82 | MEN1 (0.57) | GAAMEN1KMT2AHTTPDK1 | |
| SCHEMBL6094043 | 0.81 | TACR1 (0.42) | MEN1KMT2AMAPTHTTPDK1 | |
| SCHEMBL11775650 | 0.81 | GAA (0.49) | GAAMEN1KMT2AMAPTHTT | |
| SCHEMBL14014937 | 0.80 | MAPT (0.56) | GAAMEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5292760-A | 4-heteroaryl-1,3-benzodiazepines and 2-substituted-α-(heteroaryl)benzeneethanamines | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-08 | — | — | US | disclosed |