SCHEMBL8946170

SCHEMBL8946170

COc1cc(O)c(C=O)cc1[N+](=O)[O-]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
MAPT P10636 2/20 0.61
KDM4E B2RXH2 1/20 0.61
CYP3A4 P08684 1/20 0.61
ALOX15 P16050 1/20 0.61
PRKDC P78527 1/20 0.61
HSD17B10 Q99714 1/20 0.61
ERN1 O75460 7/20 0.55
TRIM24 O15164 1/20 0.44
TYR P14679 1/20 0.44
TRIM33 Q9UPN9 1/20 0.44
DPP4 P27487 1/20 0.43
PREP P48147 1/20 0.43
DPP9 Q86TI2 1/20 0.43
THRB P10828 1/20 0.43
KMT2A Q03164 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
XDH P47989 1/20 0.42
ALDH5A1 P51649 1/20 0.42
ABAT P80404 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19833822 0.87 ALDH1A1 (0.61) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL3847699 0.85 ALDH1A1 (0.67) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL29125349 0.82 ALDH1A1 (0.63) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL19331554 0.81 ALDH1A1 (0.77) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL2723326 0.81 ALDH1A1 (0.83) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL9005383 0.81 ALDH1A1 (0.48) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL2678872 0.81 ALDH1A1 (0.51) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL16838210 0.81 ERN1 (0.56) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL5898860 0.81 ALDH1A1 (0.76) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL20783154 0.81 ALDH1A1 (0.61) ALDH1A1MAPTKDM4ECYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113264979-B Novel method for quickly removing removable framework modification and application 中国科学技术大学 2023-06-16 CN claimed
CN-113264979-A Novel method for quickly removing framework modification and application 中国科学技术大学 2021-08-17 CN claimed
US-20250346776-A1 PHOTOHARDENABLE COMPOSITIONS AND METHODS FOR FORMING AN OBJECT IN A VOLUME OF A PHOTOHARDENABLE COMPOSITION QUADRATIC 3D INC (US) 2025-11-13 US disclosed
CN-118459535-A Polypeptide fragment connection method and polypeptide protein synthesis method 中国科学技术大学 2024-08-09 CN disclosed
CN-118076647-A Photohardenable composition and method for forming an object in the volume of the photohardenable composition 二次3D股份有限公司 2024-05-24 CN disclosed
US-20240166912-A1 PHOTOHARDENABLE COMPOSITIONS AND METHODS FOR FORMING AN OBJECT IN A VOLUME OF A PHOTOHARDENABLE COMPOSITION QUADRATIC 3D, INC. 2024-05-23 US disclosed
EP-4352114-A1 PHOTOHARDENABLE COMPOSITIONS AND METHODS FOR FORMING AN OBJECT IN A VOLUME OF A PHOTOHARDENABLE COMPOSITION Quadratic 3D, Inc. (US) 2024-04-17 EP disclosed
CN-113264979-B Novel method for quickly removing removable framework modification and application 中国科学技术大学 2023-06-16 CN disclosed
WO-2023003819-A1 PHOTOHARDENABLE COMPOSITIONS AND METHODS FOR FORMING AN OBJECT IN A VOLUME OF A PHOTOHARDENABLE COMPOSITION QUADRATIC 3D, INC. (US) 2023-01-26 WO disclosed
CN-114276430-A sDSS1 mutant protein synthesis method and purification process route thereof 上海普佑生物医药有限公司 2022-04-05 CN disclosed
CN-113264979-A Novel method for quickly removing framework modification and application 中国科学技术大学 2021-08-17 CN disclosed
EP-0511917-B1 Glycosylated prodrugs, process for their preparation and uses thereof HOECHST SA LAB (FR) 1996-10-23 EP disclosed
US-5561119-A ANTITUMOR AGENTS LABORATOIRES HOECHST (FR) 1996-10-01 US disclosed
US-5230986-A Photohardening compositions with free radical polymerizable compounds STEREOGRAPHICS LIMITED PARTNERSHIP (US) 1993-07-27 US disclosed
WO-1992019639-A1 GLYCOSYLATED PRODRUGS, METHOD OF PREPARATION AND USE LABORATOIRES HOECHST (FR) 1992-11-12 WO disclosed
EP-0511917-A1 Glycosylated prodrugs, process for their preparation and uses thereof LABORATOIRES HOECHST S.A. (FR) 1992-11-04 EP disclosed