Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | GRK6 | P43250 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946410 | 1.00 | MEN1 (0.40) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL8946407 | 1.00 | MEN1 (0.40) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL8946448 | 0.80 | MAPT (0.34) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL8946451 | 0.80 | MAPT (0.34) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL8946454 | 0.80 | MAPT (0.34) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL8946513 | 0.78 | OPRM1 (0.38) | MEN1KMT2AMAPTGAANPC1 | |
| SCHEMBL8946517 | 0.78 | OPRM1 (0.38) | MEN1KMT2AMAPTGAANPC1 | |
| SCHEMBL8946515 | 0.78 | OPRM1 (0.38) | MEN1KMT2AMAPTGAANPC1 | |
| SCHEMBL8946320 | 0.75 | OPRM1 (0.42) | MAPTGAAALDH1A1HSD17B10TP53 | |
| SCHEMBL8946330 | 0.75 | OPRM1 (0.42) | MAPTGAAALDH1A1HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |