Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946418 | 1.00 | MEN1 (0.33) | MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL8946426 | 1.00 | MEN1 (0.33) | MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL8946491 | 0.80 | — | — | |
| SCHEMBL8946499 | 0.80 | — | — | |
| SCHEMBL8946496 | 0.80 | — | — | |
| SCHEMBL10381588 | 0.73 | OPRM1 (0.39) | MEN1KMT2A | |
| SCHEMBL8946320 | 0.70 | OPRM1 (0.42) | MAPT | |
| SCHEMBL8946330 | 0.70 | OPRM1 (0.42) | MAPT | |
| SCHEMBL8946325 | 0.70 | OPRM1 (0.42) | MAPT | |
| SCHEMBL8946645 | 0.68 | MAPT (0.42) | MEN1MAPTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | disclosed |
| WO-1990015799-A1 | INDENOINDOLE COMPOUNDS II | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |