Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998335 | 0.88 | TDP1 (0.49) | KMT2ANPC1MEN1TDP1MMP8 | |
| SCHEMBL12003491 | 0.86 | MEN1 (0.53) | KMT2ANPC1MEN1TDP1MMP8 | |
| SCHEMBL27871605 | 0.86 | MEN1 (0.53) | KMT2ANPC1MEN1TDP1MMP8 | |
| SCHEMBL28573266 | 0.85 | TDP1 (0.47) | KMT2ANPC1MEN1TDP1MMP8 | |
| SCHEMBL9183767 | 0.85 | CTNNB1 (0.52) | KMT2ANPC1MEN1TDP1MAPT | |
| SCHEMBL973673 | 0.84 | KMT2A (0.69) | KMT2ANPC1MEN1TDP1MMP8 | |
| SCHEMBL27393325 | 0.83 | TDP1 (0.57) | KMT2ANPC1MEN1TDP1MMP8 | |
| SCHEMBL5450997 | 0.82 | MEN1 (0.56) | KMT2ANPC1MEN1TDP1MMP8 | |
| SCHEMBL10474638 | 0.82 | TDP1 (0.56) | KMT2ANPC1MEN1TDP1MMP8 | |
| SCHEMBL8702350 | 0.82 | MDM2 (0.51) | KMT2ANPC1MEN1TDP1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| CN-1109052-A | Pyrimidine and pyridine derivatives, their production and use | NIHON NOHYAKU CO LTD (JP) | 1995-09-27 | — | — | CN | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |