Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EIF4E | P06730 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016572 | 0.84 | MAPK14 (0.48) | KMT2ADHODHALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6016402 | 0.83 | MAPK14 (0.43) | KMT2ADHODHL3MBTL1CNR1ALDH1A1 | |
| Dimethylaminoethanol SCHEMBL6016528 | 0.81 | MAPK14 (0.46) | KMT2ADHODHALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1016143 | 0.80 | KMT2A (0.58) | KMT2ADHODHMAPTL3MBTL1CNR1 | |
| SCHEMBL5189312 | 0.79 | CNR1 (0.48) | KMT2ADHODHL3MBTL1CNR1ALDH1A1 | |
| SCHEMBL3442751 | 0.79 | ALDH1A1 (0.52) | KMT2ADHODHMAPTALDH1A1KDM4E | |
| SCHEMBL27886811 | 0.79 | CNR1 (0.43) | KMT2ADHODHL3MBTL1CNR1ALDH1A1 | |
| SCHEMBL8946526 | 0.77 | KMT2A (0.46) | KMT2ADHODHL3MBTL1CNR1ALDH1A1 | |
| SCHEMBL4111269 | 0.77 | MKNK1 (0.51) | KMT2AMAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL27471423 | 0.77 | CNR1 (0.41) | KMT2ADHODHL3MBTL1CNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |