Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10375342 | 0.99 | ATM (0.48) | ATMPOLBHTTALDH1A1MAPT | |
| SCHEMBL10375646 | 0.89 | HTT (0.48) | ATMPOLBHTTALDH1A1MAPT | |
| SCHEMBL10375645 | 0.86 | POLB (0.45) | ATMPOLBHTTALDH1A1MAPT | |
| SCHEMBL10375373 | 0.85 | ALDH1A1 (0.51) | ATMPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10376290 | 0.84 | ALDH1A1 (0.48) | ATMPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8946649 | 0.84 | ATM (0.49) | ATMPOLBHTTALDH1A1MAPT | |
| Fumaric Acid SCHEMBL10375257 | 0.81 | ALDH1A1 (0.49) | ATMPOLBALDH1A1MAPTSMN1; SMN2 | |
| Fumaric Acid SCHEMBL10375258 | 0.81 | ALDH1A1 (0.49) | ATMPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10376593 | 0.80 | ALDH1A1 (0.52) | POLBHTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10376555 | 0.79 | MAPT (0.45) | ATMPOLBHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |