Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PTPRC | P08575 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2511483 | 0.84 | CYP3A4 (0.42) | GABRA1GABRB2CYP3A4 | |
| SCHEMBL2727862 | 0.84 | GABRA1 (0.40) | GABRA1GABRB2CYP3A4MAPK1TDP1 | |
| SCHEMBL3862629 | 0.80 | SMN1; SMN2 (0.38) | GABRA1GABRB2CYP3A4MEN1KMT2A | |
| SCHEMBL1201225 | 0.76 | CYP3A4 (0.46) | GABRA1GABRB2CYP3A4TSHRMEN1 | |
| SCHEMBL428210 | 0.76 | CYP3A4 (0.38) | GABRA1GABRB2CYP3A4TDP1ALDH1A1 | |
| SCHEMBL1170136 | 0.72 | GABRA1 (0.48) | GABRA1GABRB2CYP3A4TSHRKMT2A | |
| SCHEMBL3257470 | 0.72 | CYP3A4 (0.39) | GABRA1GABRB2CYP3A4NPC1RAB9A | |
| SCHEMBL6855581 | 0.71 | CYP3A4 (0.52) | GABRA1GABRB2CYP3A4TSHRMEN1 | |
| SCHEMBL10958805 | 0.70 | DNMT1 (0.34) | GABRA1GABRB2 | |
| SCHEMBL112824 | 0.70 | CYP3A4 (0.56) | GABRA1GABRB2CYP3A4TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565508-A | USEFUL AS BINDERS IN ELECTRODEPOSITION COATING BATHS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | disclosed |