Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14985854 | 0.83 | EGFR (0.35) | EGFRDPP4 | |
| SCHEMBL12370927 | 0.82 | EGFR (0.32) | EGFRDPP4 | |
| SCHEMBL3716819 | 0.82 | MAPK1 (0.32) | EGFRDPP4 | |
| SCHEMBL14850750 | 0.79 | NPSR1 (0.39) | EGFR | |
| SCHEMBL8773533 | 0.73 | — | — | |
| SCHEMBL3824054 | 0.71 | SMN1; SMN2 (0.42) | L3MBTL1 | |
| SCHEMBL23819354 | 0.69 | — | — | |
| SCHEMBL25252963 | 0.67 | — | — | |
| SCHEMBL16254891 | 0.67 | SMN1; SMN2 (0.49) | L3MBTL1 | |
| SCHEMBL8947247 | 0.67 | CNR2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583092-A | PLANT ANTIGROWTH AGENTS | AMERICAN CYANAMID COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| CN-1134936-A | Herbicidal (1,2,4) thiadiazoles | AMERICAN CYANAMID CO (US) | 1996-11-06 | — | — | CN | disclosed |
| EP-0726261-A1 | Herbidical 1,2,4 thiadiazoles | American Cyanamid Company (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0726260-A1 | Herbicidal (1,2,4)thiadiazoles | AMERICAN CYANAMID COMPANY (US) | 1996-08-14 | — | — | EP | disclosed |