Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 8/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | IDH2 | P48735 | 4/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17960860 | 0.73 | ADORA3 (0.54) | KMT2AADORA3ADORA2AALDH1A1 | |
| SCHEMBL3647705 | 0.72 | SMN1; SMN2 (0.56) | KMT2AADORA3TSHRKDM4EALOX15 | |
| SCHEMBL27508760 | 0.68 | CYP19A1 (0.48) | GAAKMT2AADORA3ALDH1A1TSHR | |
| SCHEMBL16369842 | 0.67 | IDH1 (0.44) | IDH1IDH2ADORA2A | |
| SCHEMBL30492599 | 0.66 | CYP3A4 (0.50) | IDH1KMT2AIDH2ALDH1A1TSHR | |
| SCHEMBL1071454 | 0.66 | CYP3A4 (0.50) | IDH1KMT2AIDH2ALDH1A1TSHR | |
| SCHEMBL25252963 | 0.66 | — | — | |
| SCHEMBL7694980 | 0.65 | TSHR (0.50) | GAAKMT2AALDH1A1TSHRCYP3A4 | |
| SCHEMBL29763431 | 0.64 | IDH1 (0.47) | IDH1IDH2ADORA2ATSHRCYP3A4 | |
| SCHEMBL16369763 | 0.64 | IDH1 (0.47) | IDH1IDH2ADORA2ATSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583092-A | PLANT ANTIGROWTH AGENTS | AMERICAN CYANAMID COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| CN-1134936-A | Herbicidal (1,2,4) thiadiazoles | AMERICAN CYANAMID CO (US) | 1996-11-06 | — | — | CN | disclosed |
| EP-0726260-A1 | Herbicidal (1,2,4)thiadiazoles | AMERICAN CYANAMID COMPANY (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0726261-A1 | Herbidical 1,2,4 thiadiazoles | American Cyanamid Company (US) | 1996-08-14 | — | — | EP | disclosed |