Demannose

Demannose

SCHEMBL8947229

C=COC=C.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
PDE4A P27815 1/20 0.36
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
AKR1B1 P15121 1/20 0.33
KDM4E B2RXH2 2/20 0.32
MPI P34949 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demannose SCHEMBL28302746 0.86 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL28021322 0.86 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL5214056 0.86 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL27810472 0.86 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL608517 0.86 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL25327742 0.86 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL525084 0.85 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL15321015 0.85 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL13947310 0.85 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL14486320 0.85 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5576407-A Copolymers of hydroxyalkyl vinyl ethers for use in detergents and cleaning agents BASF AKTIENGESELLSCHAFT (DE) 1996-11-19 US disclosed