SCHEMBL894735

SCHEMBL894735

NC(=O)N=Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 2/20 0.52
GRIN3B O60391 2/20 0.52
GRIN1 Q05586 2/20 0.52
GRIN2A Q12879 2/20 0.52
GRIN2B Q13224 2/20 0.52
GRIN2C Q14957 2/20 0.52
GRIN3A Q8TCU5 2/20 0.52
TAAR1 Q96RJ0 1/20 0.52
LMNA P02545 3/20 0.52
MAPT P10636 3/20 0.52
ALDH1A1 P00352 2/20 0.52
KDM4E B2RXH2 1/20 0.52
HPGD P15428 1/20 0.52
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
PLA2G7 Q13093 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.48
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CYP1A2 P05177 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19803821 0.82 GRIN2D (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2367422 0.81 MEN1 (0.54) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2367424 0.81 MEN1 (0.54) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL8635101 0.81 MEN1 (0.54) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL8635103 0.81 MEN1 (0.54) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL5551423 0.78 MEN1 (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL16861633 0.77 GRIN1 (0.52) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Benzaldehyde Oxime SCHEMBL10332555 0.77 KMT2A (0.57) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL3067089 0.77 MEN1 (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL887433 0.77 MEN1 (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 383 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638538-A1 LIQUID RHEOLOGY CONTROL AGENT BYK-Chemie GmbH (DE) 2025-10-29 EP claimed
WO-2024133435-A1 LIQUID RHEOLOGY CONTROL AGENT BYK-CHEMIE GMBH (DE) 2024-06-27 WO claimed
EP-2998435-B1 PHOSPHORIC ACID ESTERIFIED CELLULOSE FIBERS AND PRODUCTION METHOD THEREOF OJI HOLDINGS CORP (JP) 2021-10-13 EP claimed
EP-2592069-B1 METHOD OF PRODUCING TOLUENEDICARBAMATE AND METHOD OF PRODUCING TOLUENEDIISOCYANATE MITSUI CHEMICALS INC (JP) 2019-04-24 EP claimed
CN-102933545-B Method of producing toluene dicarbamate, method of producing toluene diisocyanate, and toluene dicarbamate MITSUI CHEMICALS INC 2014-11-12 CN claimed
US-8742164-B2 Method for producing toluenedicarbamate, method for producing toluenediisocyanate, and toluenedicarbamate MITSUI CHEMICALS, INC. (JP) 2014-06-03 US claimed
US-8580875-B2 Acrylic emulsion polymers for removable pressure sensitive adhesive applications ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) 2013-11-12 US claimed
EP-2592069-A1 METHOD OF PRODUCING TOLUENEDICARBAMATE, METHOD OF PRODUCING TOLUENEDIISOCYANATE, AND TOLUENEDICARBAMATE Mitsui Chemicals, Inc. (JP) 2013-05-15 EP claimed
US-20130109881-A1 METHOD FOR PRODUCING TOLUENEDICARBAMATE, METHOD FOR PRODUCING TOLUENEDIISOCYANATE, AND TOLUENEDICARBAMATE MITSUI CHEMICALS, INC. 2013-05-02 US claimed
CN-102933545-A Method of producing toluene dicarbamate, method of producing toluene diisocyanate, and toluene dicarbamate MITSUI CHEMICALS INC 2013-02-13 CN claimed
US-6479508-B1 INHIBITOR OF RNA DEPENDENT RNA POLYMERASE ACTIVITY OF THE ENZYME NS5B ENCODED BY HEPATITIS C VIRUS FOR TREATMENT AND PREVENTION OF HEPATITIS C INFECTIONS BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 2002-11-12 US claimed
WO-2002085838-A1 COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2002-10-31 WO claimed
US-6448281-B1 INHIBITORS OF HEPATITIS C VIRUS REPLICATION; TREATMENT OF HEPATITIS C BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 2002-09-10 US claimed
US-20020065418-A1 Inhibitors of hepatitis C virus replication; treatment of hepatitis C BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 2002-05-30 US claimed
US-6358975-B1 ADMINISTERING 3,4-DIHYDRO-5-(4-(1-PIPERIDINYL)-BUTOX)-1 (2H)-ISOQUINOLINONE, A SELECTIVE INHIBITOR OF POLY(ADP-RIBOSE) POLYMERASE FOR PROPHYLAXIS OF NEURAL TISSUE DAMAGE RESULTING FROM ISCHEMIA AND REPERFUSION INJURY OR NEURODEGENERATIVE JOHNS HOPKINS UNIVERSITY 2002-03-19 US claimed
WO-2002004425-A2 VIRAL POLYMERASE INHIBITORS BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 2002-01-17 WO claimed
US-5874444-A CONTROLLING CELL AGING GERON CORPORATION (US) 1999-02-23 US claimed
WO-1998027975-A1 POLY(ADP-RIBOSE) POLYMERASE INHIBITORS TO TREAT DISEASES ASSOCIATED WITH CELLULAR SENESCENCE GERON CORPORATION (US) 1998-07-02 WO claimed
US-5521315-A Olefin substituted long chain compounds CELL THERAPEUTICS, INC. (US) 1996-05-28 US claimed
EP-0638309-A1 Substances inhibiting proteic adp ribosilation suitable to prevent the diabetes mellitus complications ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.p.A. (IT) 1995-02-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020065418-A1 Inhibitors of hepatitis C virus replication; treatment of hepatitis C HAVCR2, HCCS, ZC3HAV1 GRIN2D 4626/4885GRIN3B 2732/4885GRIN1 2546/4885
US-20130109881-A1 METHOD FOR PRODUCING TOLUENEDICARBAMATE, METHOD FOR PRODUCING TOLUENEDIISOCYANATE, AND TOLUENEDICARBAMATE CPS1, TST, ALKBH3 GRIN2D 4219/4885GRIN3B 4757/4885GRIN1 4218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.