SCHEMBL8947717

SCHEMBL8947717

C[SiH](C)O[Si](C)(C)CCCOc1cccc(N)c1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.54
CYP3A4 P08684 2/20 0.49
TP53 P04637 1/20 0.49
MAOB P27338 2/20 0.42
ALDH1A1 P00352 1/20 0.41
APP P05067 1/20 0.39
LTA4H P09960 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28343911 0.93 TSHR (0.51) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL893806 0.85 TSHR (0.59) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL8361890 0.84 TSHR (0.58) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL27601560 0.84 CYP3A4 (0.53) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL8671106 0.81 TSHR (0.62) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL961436 0.78 TSHR (0.58) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL894725 0.77 TSHR (0.57) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL10594544 0.77 TSHR (0.56) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL109946 0.76 TSHR (0.59) TSHRCYP3A4TP53MAOBALDH1A1
SCHEMBL30781624 0.76 TSHR (0.59) TSHRCYP3A4TP53MAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110568741-A Intermediate transfer belt and image forming apparatus 柯尼卡美能达株式会社 2019-12-13 CN disclosed
US-5512628-A COMBINING A PIPERAZINYLETHYLAMINOCARBONYL-CONTAINING BUTADIENE-ACRYLONITRILE COPOLYMER WITH A MALEIMIDE CONTAINING COMPOUND IN AN ORGANIC SOLVENT; CURABLE TOMOEGAWA PAPER CO., LTD. (JP) 1996-04-30 US disclosed
US-5510189-A COMPRISING A PIPERAZINYLETHYLAMINOCARBONYL-CONTAINING BUTADIENE-ACRYLONITRILE COPOLYMER AND A MALEIMIDE COMPOUND; ADHERED AND CURED AT LOW TEMPERATURE; HEAT RESISTANCE TOMOEGAWA PAPER CO., LTD. (JP) 1996-04-23 US disclosed