Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298314 | 0.86 | F2 (0.42) | F2KCNA5HPGDPRSS1 | |
| SCHEMBL8947704 | 0.85 | F2 (0.43) | F2KCNA5HPGDPRSS1CYP3A4 | |
| SCHEMBL7297129 | 0.85 | F2 (0.43) | F2KCNA5HPGDPRSS1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8947655 | 0.82 | F2 (0.49) | F2 | |
| SCHEMBL8947782 | 0.78 | F2 (0.35) | F2KCNA5HPGDCYP3A4CYP2D6 | |
| SCHEMBL8947700 | 0.76 | F2 (0.35) | F2KCNA5HPGDCYP3A4CYP2D6 | |
| SCHEMBL9164171 | 0.75 | F2 (0.54) | F2 | |
| SCHEMBL8947690 | 0.71 | F2 (0.46) | F2 | |
| SCHEMBL8947678 | 0.71 | F2 (0.46) | F2 | |
| Trifluoroacetic Acid SCHEMBL8947764 | 0.71 | F2 (0.33) | F2KCNA5PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578594-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5405854-A | Anticoagulants | HOFFMANN-LA ROCHE INC. (US) | 1995-04-11 | — | — | US | disclosed |