SCHEMBL8948043

SCHEMBL8948043

CCCCCC(C)/C=C/C(C)=O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.44
MAPT P10636 2/20 0.40
ACE2 Q9BYF1 1/20 0.40
TRPA1 O75762 1/20 0.40
DDAH1 O94760 1/20 0.40
GAPDH P04406 1/20 0.40
GPR84 Q9NQS5 3/20 0.39
FFAR1 O14842 1/20 0.39
ZDHHC7 Q9NXF8 1/20 0.39
TP53 P04637 1/20 0.38
LCK P06239 1/20 0.38
PPARD Q03181 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
FAAH O00519 1/20 0.38
PPARG P37231 2/20 0.37
GPR132 Q9UNW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8948047 1.00 CA1 (0.44) CA1MAPTACE2TRPA1DDAH1
SCHEMBL8948019 0.98 ACE2 (0.43) CA1MAPTACE2GPR84FFAR1
SCHEMBL8948016 0.98 ACE2 (0.43) CA1MAPTACE2GPR84FFAR1
SCHEMBL8948270 0.94 ACHE (0.42) CA1MAPTACE2TRPA1DDAH1
SCHEMBL8948267 0.94 ACHE (0.42) CA1MAPTACE2TRPA1DDAH1
SCHEMBL809574 0.85 CHRM1 (0.36) CA1
SCHEMBL814572 0.85 CHRM1 (0.36) CA1
SCHEMBL5666704 0.85 CHRM1 (0.36) CA1
SCHEMBL30527786 0.84 ACHE (0.49) CA1MAPTACE2GPR84FFAR1
SCHEMBL29177079 0.82 ACHE (0.47) CA1MAPTACE2GPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5484949-A Method for the synthesis of α β-unsaturated ketones NIPPON SODA CO., LTD. (JP) 1996-01-16 US disclosed
EP-0454867-A1 A METHOD FOR THE SYNTHESIS OF -g(a), -g(b)-UNSATURATED KETONES. NIPPON SODA CO (JP) 1991-11-06 EP disclosed
WO-1991007370-A1 A METHOD FOR THE SYNTHESIS OF α, β-UNSATURATED KETONES NIPPON SODA CO., LTD. (JP) 1991-05-30 WO disclosed