Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101000 | 0.93 | ERN1 (0.54) | ERN1CYP2A6CYP3A4ALDH1A1CYP1A2 | |
| Pyrrole SCHEMBL28357672 | 0.91 | ERN1 (0.49) | ERN1CYP2A6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL30252276 | 0.85 | ERN1 (0.57) | ERN1CYP2A6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL14840485 | 0.85 | ERN1 (0.57) | ERN1CYP2A6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL6688459 | 0.83 | CDK4 (0.47) | ERN1CYP2A6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL11071868 | 0.83 | ERN1 (0.51) | ERN1CYP2A6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL10960411 | 0.81 | CYP2A6 (0.50) | ERN1CYP2A6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL612568 | 0.81 | ERN1 (0.47) | ERN1CYP2A6ALDH1A1XDHLMNA | |
| SCHEMBL30302117 | 0.80 | ERN1 (0.59) | ERN1CYP2A6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL1802008 | 0.80 | ERN1 (0.59) | ERN1CYP2A6CYP3A4ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187220-A | Trifluoromethyl pyrimidine derivative containing Schiff base structural unit and preparation method and application thereof | 郑州大学 | 2020-05-22 | — | — | CN | claimed |
| CN-110483507-A | A kind of synthetic method of naphtho- [1 ', 2 ': 4,5] imidazo [1,2-a] pyridine compounds and their | UNIV HENAN NORMAL | 2019-11-22 | — | — | CN | claimed |
| CN-105017350-B | A kind of glycosyl pyridine compounds and their and its preparation and application | 杭州师范大学 | 2018-03-16 | — | — | CN | claimed |
| CN-105037352-A | Synthetic method of 8-methoxyphenyl ketone imidazo[1,2a]pyridine-3-phenyl ketone | SHANDONG YOUBANG BIOCHEMICAL TECHNOLOGY CO LTD | 2015-11-11 | — | — | CN | claimed |
| CN-105017350-A | Sugar-based pyridine type compound as well as preparation method and application thereof | UNIV HANGZHOU NORMAL | 2015-11-04 | — | — | CN | claimed |
| CN-104910152-A | 6-Bromo-8-methoxy-phenyl ketone imidazo [1,2a] pyridin-3-phenyl ketone synthetic method | SHANDONG YOUBANG BIOCHEMICAL TECHNOLOGY CO LTD | 2015-09-16 | — | — | CN | claimed |
| CN-104844596-A | Synthesis method for 6-bromoimidazo[1, 2-a]pyridine-3-phenyl ketone | SHANDONG YOUBANG BIOCHEMICAL TECHNOLOGY CO LTD | 2015-08-19 | — | — | CN | claimed |
| CN-104844595-A | Synthesis method for imidazo[1, 2-a]pyridine-3-phenyl ketone | SHANDONG YOUBANG BIOCHEMICAL TECHNOLOGY CO LTD | 2015-08-19 | — | — | CN | claimed |
| CN-104829615-A | Synthesis method for 6-fluoroimidazo[1, 2-a]pyridine-3-phenyl ketone | SHANDONG YOUBANG BIOCHEMICAL TECHNOLOGY CO LTD | 2015-08-12 | — | — | CN | claimed |
| CN-104829617-A | Synthesis method for 6-fluoroimidazo[1, 2-a]pyridine-3-carbonitrile | SHANDONG YOUBANG BIOCHEMICAL TECHNOLOGY CO LTD | 2015-08-12 | — | — | CN | claimed |
| CN-104829616-A | Synthesis method for 6-chloroimidazo[1, 2-a]pyridine-3-phenyl ketone | SHANDONG YOUBANG BIOCHEMICAL TECHNOLOGY CO LTD | 2015-08-12 | — | — | CN | claimed |
| CN-103435609-A | Copper-catalyzed synthetic method of imidazo[1,2-a]pyridine-3-formaldehyde compound | UNIV NORTHEAST NORMAL | 2013-12-11 | — | — | CN | claimed |
| CN-102153539-A | 3-aminopyrrolidine derivatives as modulators of chemokine receptors | INCYTE CORP | 2011-08-17 | — | — | CN | claimed |
| CN-115093410-B | Preparation method of beta-carboline compound | 南京工业大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-111187220-B | Trifluoromethyl pyrimidine derivative containing Schiff base structural unit and preparation method and application thereof | 郑州大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-113801033-B | Synthesis method of 2-aminoindan or derivatives thereof | 苏州欣诺科生物科技有限公司 | 2022-02-08 | — | — | CN | disclosed |
| EP-0879814-A1 | Triaromatic compounds, compositions containing them and uses thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-11-25 | — | — | EP | disclosed |
| EP-0148826-A1 | FUNGICIDAL, HERBICIDAL AND PLANT GROWTH REGULATING PYRIDYL-CONTAINING ETHERS | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1985-07-24 | — | — | EP | disclosed |
| WO-1985000289-A1 | FUNGICIDAL, HERBICIDAL AND PLANT GROWTH REGULATING PYRIDYL-CONTAINING ETHERS | CHEVRON RESEARCH COMPANY (US) | 1985-01-31 | — | — | WO | disclosed |
| US-4407806-A | PRE- AND POSTEMERGENCE HERBICIDES | CHEVRON RESEARCH COMPANY (US) | 1983-10-04 | — | — | US | disclosed |