Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | FDPS | P14324 | 4/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947308 | 0.82 | SPHK1 (0.52) | MAPTGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL3955215 | 0.82 | SPHK1 (0.52) | MAPTGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL11658003 | 0.79 | MAPT (0.44) | MAPTGPR84FDPSSPHK1FFAR1 | |
| SCHEMBL21593940 | 0.78 | MAPT (0.52) | MAPTGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL21593936 | 0.78 | MAPT (0.52) | MAPTGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL21593937 | 0.76 | SPHK1 (0.45) | MAPTGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL21593938 | 0.76 | SPHK1 (0.45) | MAPTGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL8948112 | 0.76 | GPR84 (0.61) | MAPTGPR84FFAR1 | |
| SCHEMBL8948179 | 0.76 | MAPT (0.44) | MAPTGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL5180208 | 0.75 | GPR84 (0.55) | MAPTGPR84FDPSSPHK1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519128-A | Process for the synthesis of acylated derivatives of fatty acid-transporting thiols and in particular acyl-coenzymes A and the thus obtained acyl-coenzymes A | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1996-05-21 | — | — | US | claimed |
| EP-0618218-A1 | Process for synthesising fatty acid acylated thiol transporter derivative, particularly of acyl coenzyme A derivatives, and the acyl-coenzyme A derivatives thus obtained | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1994-10-05 | — | — | EP | claimed |