Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.57 |
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870425 | 0.88 | SIGMAR1 (0.53) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| SCHEMBL9437778 | 0.86 | SIGMAR1 (0.51) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| SCHEMBL9685601 | 0.86 | SIGMAR1 (0.60) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| SCHEMBL9437943 | 0.85 | SIGMAR1 (0.50) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437727 | 0.85 | SIGMAR1 (0.50) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437816 | 0.85 | SIGMAR1 (0.52) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9484568 | 0.85 | SIGMAR1 (0.62) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| SCHEMBL9437813 | 0.84 | MAOB (0.47) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9685737 | 0.83 | SIGMAR1 (0.64) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| SCHEMBL9437854 | 0.83 | SIGMAR1 (0.47) | SIGMAR1HTR1AHTR2CADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512569-A | SIGMA RECEPTOR DISORDERS; PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1996-04-30 | — | — | US | disclosed |