Styrene

Styrene

SCHEMBL8948456

C=CCCc1ccccc1.C=Cc1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
TSHR P16473 1/20 0.58
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
CYP2A6 P11509 1/20 0.38
HTR2A P28223 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
GPR52 Q9Y2T5 2/20 0.38
MAOB P27338 2/20 0.36
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49747 0.89 ALDH1A1 (0.48) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL28658494 0.87 ALDH1A1 (0.46) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL28363765 0.87 ALDH1A1 (0.46) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL7572069 0.87 ALDH1A1 (0.46) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL16681696 0.87 ALDH1A1 (0.46) ALDH1A1HPGDALOX15ALOX12CASP1
Methane SCHEMBL27454678 0.87 ALDH1A1 (0.46) ALDH1A1HPGDALOX15ALOX12CASP1
Ammonia Solution, Strong SCHEMBL11487919 0.87 ALDH1A1 (0.46) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL346414 0.85 ALDH1A1 (0.52) ALDH1A1TSHRALOX15ALOX12TDP1
Styrene SCHEMBL20153440 0.84 ALDH1A1 (0.74) ALDH1A1TSHRTDP1CYP2A6MAOB
Styrene SCHEMBL364050 0.84 ALDH1A1 (0.74) ALDH1A1TSHRTDP1CYP2A6MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5518626-A Process employing thermally sterilizable aqueous polishing agents UNITED TECHNOLOGIES CORPORATION (US) 1996-05-21 US claimed
WO-1995017251-A1 SYSTEM AND PROCESS FOR REMOVING FREE AND DISSOLVED CO2 FROM AQUEOUS SOLUTIONS UNITED TECHNOLOGIES CORPORATION (US) 1995-06-29 WO claimed
WO-1995017250-A1 SYSTEM AND PROCESS EMPLOYING THERMALLY STERILIZABLE AQUEOUS POLISHING AGENTS UNITED TECHNOLOGIES CORPORATION (US) 1995-06-29 WO claimed