Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30566393 | 0.81 | CTNNB1 (0.34) | PARP1HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL1142545 | 0.81 | CTNNB1 (0.34) | PARP1HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL15800560 | 0.78 | ACHE (0.38) | ACHEPARP1HTR2AHTR2CHTR2B | |
| SCHEMBL25166676 | 0.78 | HTR2A (0.32) | HTR2AHTR2CHTR2BHTR1ACTNNB1 | |
| SCHEMBL23870268 | 0.78 | HTR2A (0.32) | HTR2AHTR2CHTR2BHTR1ACTNNB1 | |
| SCHEMBL30507850 | 0.76 | MAPT (0.34) | ACHE | |
| SCHEMBL29054691 | 0.76 | MAPT (0.34) | ACHE | |
| SCHEMBL14070899 | 0.75 | HTR2A (0.30) | HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL14070891 | 0.75 | KCNH2 (0.33) | ACHEHTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL1812982 | 0.73 | ACHE (0.42) | ACHEPARP1HTR2AHTR2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521147-A | HERBICIDES | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |