Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948882 | 0.87 | ITGB3 (0.61) | F10F2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8312680 | 0.86 | F10 (0.42) | F10F2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8948753 | 0.86 | GRM2 (0.51) | F10F2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8948802 | 0.83 | F10 (0.51) | F10F2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8315140 | 0.83 | F10 (0.41) | F10F2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8948680 | 0.83 | F10 (0.58) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL8948785 | 0.83 | F10 (0.58) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL8948704 | 0.83 | F10 (0.58) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL8948886 | 0.80 | ITGB3 (0.46) | F10F2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8312681 | 0.80 | F10 (0.40) | F10F2ITGB3ITGA2BPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |