Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 6/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948690 | 0.91 | GRM2 (0.48) | GRM2SIGMAR1PPARGPPARDPPARA | |
| SCHEMBL8948659 | 0.88 | GRM2 (0.48) | GRM2HRH3SIGMAR1MEN1 | |
| SCHEMBL8948544 | 0.84 | GRM2 (0.43) | GRM2SIGMAR1MEN1 | |
| SCHEMBL8948799 | 0.82 | GRM2 (0.44) | GRM2SIGMAR1 | |
| SCHEMBL8948624 | 0.82 | GRM2 (0.52) | GRM2SIGMAR1 | |
| SCHEMBL8948674 | 0.79 | GRM2 (0.46) | GRM2SIGMAR1 | |
| SCHEMBL8948811 | 0.78 | GRM2 (0.48) | GRM2SIGMAR1F10 | |
| SCHEMBL8316229 | 0.78 | GRM2 (0.51) | GRM2SIGMAR1F10 | |
| SCHEMBL8948767 | 0.78 | GRM2 (0.48) | GRM2SIGMAR1 | |
| SCHEMBL8948841 | 0.77 | GRM2 (0.47) | GRM2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |