Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948703 | 0.87 | SIGMAR1 (0.36) | GRM2SIGMAR1 | |
| SCHEMBL8948841 | 0.87 | GRM2 (0.47) | GRM2SIGMAR1 | |
| SCHEMBL8948800 | 0.85 | GRM2 (0.46) | GRM2SIGMAR1 | |
| SCHEMBL8948884 | 0.84 | GRM2 (0.43) | GRM2SIGMAR1 | |
| SCHEMBL8948767 | 0.83 | GRM2 (0.48) | GRM2SIGMAR1 | |
| SCHEMBL8948690 | 0.82 | GRM2 (0.48) | GRM2SIGMAR1 | |
| SCHEMBL8948853 | 0.82 | GRM2 (0.44) | GRM2SIGMAR1 | |
| SCHEMBL8948654 | 0.80 | RECQL (0.36) | GRM2SIGMAR1 | |
| SCHEMBL8948845 | 0.80 | GRM2 (0.51) | GRM2SIGMAR1 | |
| SCHEMBL8948736 | 0.80 | GRM2 (0.48) | GRM2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |