SCHEMBL8948865

SCHEMBL8948865

O=C(O)/C=C/C(=O)OS(=O)(=O)O

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 12/20 0.48
TSHR P16473 2/20 0.45
TP53 P04637 1/20 0.45
EGLN1 Q9GZT9 1/20 0.45
EGLN3 Q9H6Z9 1/20 0.45
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ATM Q13315 1/20 0.32
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
ALOX15 P16050 1/20 0.31
RECQL P46063 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1425276 1.00 HCAR2 (0.48) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL1425277 1.00 HCAR2 (0.48) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL28579726 0.98 HCAR2 (0.46) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL1425274 0.89 HCAR2 (0.38) HCAR2TSHRTDP1KEAP1NFE2L2
SCHEMBL6095333 0.89 HCAR2 (0.38) HCAR2TSHRTDP1KEAP1NFE2L2
Ammonia Solution, Strong SCHEMBL29112117 0.82 KEAP1 (0.33) HCAR2KEAP1NFE2L2CA2
SCHEMBL3176632 0.78 HCAR2 (0.52) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL28733317 0.75 TSHR (0.33) TSHRTDP1CA2
Fumaric Acid SCHEMBL6095324 0.74 TSHR (0.69) HCAR2TSHRTP53EGLN1EGLN3
Fumaric Acid SCHEMBL6095338 0.74 TSHR (0.69) HCAR2TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102639568-A Functionalized polymers and methods for their manufacture BRIDGESTONE CORP 2012-08-15 CN claimed
CN-105359306-A Actinic and electron beam radiation curable water based electrode binders and electrodes incorporating same MILTEC CORP 2016-02-24 CN disclosed
CN-102639568-B Functionalized polymers and methods for their manufacture BRIDGESTONE CO.,LTD. (JP) 2014-10-22 CN disclosed
CN-101918466-B Radiation curable compositions CYTEC SURFACE SPECIALTIES SA 2013-01-30 CN disclosed
CN-102639568-A Functionalized polymers and methods for their manufacture BRIDGESTONE CORP 2012-08-15 CN disclosed
CN-101918466-A Radiation curable compositions CYTEC SURFACE SPECIALTIES SA 2010-12-15 CN disclosed
US-5488146-A SULFONATING MALEIC ANHYDRIDE WITH SULFUR TRIOXIDE; ADDING GLYCOLIC ACID; SALT FORMATION WITH ALKALINE EARTH OR ALKALI METAL HYDROXIDE; PRECIPITATING; ION EXCHANGING WITH SODIUM SALT LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1996-01-30 US disclosed