Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 16/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949101 | 0.95 | FPR2 (0.33) | FPR2KDM1A | |
| SCHEMBL8949048 | 0.94 | FPR2 (0.34) | FPR2KDM1A | |
| SCHEMBL8949133 | 0.94 | FPR2 (0.33) | FPR2 | |
| SCHEMBL8949154 | 0.94 | FPR2 (0.33) | FPR2 | |
| SCHEMBL8949059 | 0.94 | FPR2 (0.33) | FPR2 | |
| SCHEMBL8949094 | 0.94 | FPR2 (0.33) | FPR2 | |
| SCHEMBL8949049 | 0.93 | KDM1A (0.37) | FPR2KDM1A | |
| SCHEMBL13000157 | 0.89 | FPR2 (0.31) | FPR2 | |
| SCHEMBL8948786 | 0.89 | FPR2 (0.37) | FPR2KDM1APDE4BGABRA1GABRB2 | |
| SCHEMBL8940420 | 0.88 | FPR2 (0.33) | FPR2KDM1AGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |