Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25928005 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL13240737 | 0.87 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL1543215 | 0.87 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| Hydrochloric Acid SCHEMBL1543621 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| Hydrochloric Acid SCHEMBL1543620 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL2370606 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL29173102 | 0.85 | MEN1 (0.51) | ALDH1A1GRIN2BKMT2AMEN1SLC18A3 | |
| SCHEMBL1536103 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL31630375 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL1536115 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |