Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.47 |
| ▸ | CNR1 | P21554 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8949174 | 0.87 | CNR2 (0.46) | CNR2CNR1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL8949296 | 0.86 | CNR2 (0.60) | CNR2CNR1SMN1; SMN2CRHR1CRHR2 | |
| SCHEMBL8949025 | 0.85 | CNR2 (0.47) | CNR2CNR1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL8949399 | 0.82 | CNR2 (0.49) | CNR2CNR1HPGDSMN1; SMN2CRHR1 | |
| SCHEMBL8949206 | 0.81 | CNR2 (0.46) | CNR2CNR1HPGDSMN1; SMN2CRHR1 | |
| SCHEMBL8949199 | 0.79 | ITGB3 (0.43) | CNR2CNR1HPGDF10 | |
| SCHEMBL8949357 | 0.79 | CNR2 (0.59) | CNR2CNR1SMN1; SMN2CRHR1CRHR2 | |
| SCHEMBL8949091 | 0.79 | CNR1 (0.48) | CNR2CNR1SMN1; SMN2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL8949111 | 0.78 | ITGB3 (0.43) | CNR2CNR1HPGDF10 | |
| SCHEMBL8949106 | 0.78 | CNR2 (0.56) | CNR2CNR1SMN1; SMN2CRHR1CRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |