Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 19/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949136 | 0.95 | ITGB3 (0.54) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL8949010 | 0.89 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL8863340 | 0.88 | ITGB3 (0.61) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8410466 | 0.87 | ITGB3 (0.60) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8949069 | 0.86 | ITGB3 (0.43) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL8949209 | 0.83 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL8949071 | 0.82 | ITGB3 (0.53) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8949289 | 0.82 | ITGB3 (0.45) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL8410417 | 0.81 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL8949202 | 0.81 | ITGB3 (0.49) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |