Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948999 | 0.97 | ITGB3 (0.41) | NR1H4HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL8949139 | 0.94 | KDM5B (0.39) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL8949063 | 0.90 | ITGB3 (0.47) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL8949033 | 0.87 | ITGB3 (0.51) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL8949239 | 0.86 | ITGB3 (0.45) | F10ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8949090 | 0.86 | F10 (0.37) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL8949257 | 0.85 | HDAC3 (0.39) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL8949124 | 0.85 | HDAC3 (0.39) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL8949390 | 0.84 | HDAC6 (0.41) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL8949365 | 0.84 | F2 (0.39) | ALDH1A1SMN1; SMN2F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |